GLP-1 Care

GLP-1s do more than curb appetite

GLP-1s affect systems across your whole body. Third Avenue helps you unlock their full potential with doctor-led care, personalized dosing, and ongoing support.

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Biomarker-informed care Personalized dosing Ongoing support 4.9/5 patient rating Trusted by thousands

How GLP-1s work

GLP-1s act across key systems in your body

GLP-1 receptors are found across the brain, heart, liver, kidneys, pancreas, and muscle. By acting on these pathways, GLP-1s can improve metabolism, lower inflammation, and help protect organ function—which is why we treat them as tools for long-term health, not quick fixes.

Improve metabolism

GLP-1s improve insulin sensitivity and glucose control, supporting steadier energy and healthier metabolic function over time.

Protect organ function

By acting on receptors in the heart, liver, and kidneys, GLP-1s have been studied for protective effects across multiple organ systems.

Lower inflammation

GLP-1 signaling has been linked to reduced systemic inflammation, a key driver of aging and chronic disease.

Medications that affect the whole body require ongoing care. Without oversight, early changes can be missed and long-term results compromised. Third Avenue stays with you the whole way.

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0–6mo

critical window

The first months set the foundation—dosing, tolerance, and progress need active guidance.

2×

longer on therapy

Ongoing support keeps patients on GLP-1s about twice as long, maximizing the benefits.

9+

systems affected

GLP-1s influence the brain, heart, kidneys, and more—worth tracking across the body.

85%

muscle preserved

With guidance and protein-forward protocols, patients protect lean muscle while losing fat.

Most GLP-1 programs fall short

Typical programs

Multi-system care

Success measured across your whole body, not just the scale

Clinician-led oversight

Dosing, tolerance, and response actively managed over time

Muscle preservation

Protein and strength guidance to protect lean mass

Side-effect support

Real help with nausea and GI symptoms so you stay consistent

Long-term results

Built to support lasting metabolic health, not a quick fix

Clinician-guided GLP-1 treatment

I message my care team about my dosing and how I'm feeling, and they actually adjust my plan around it. I've seen real changes in my bloodwork and how I feel day to day.
Kenji T.

Kenji T.

Third Avenue patient

Your action plan

Science-backed strategies to get the most from GLP-1s

Medication is only part of the picture. Your care team pairs it with practical, evidence-based guidance so results last.

Protein & nutrition

Hit daily protein targets to preserve muscle and improve body composition while you lose weight.

Muscle preservation

Strength-training guidance and progress tracking help you maintain lean mass—the key to healthy aging.

Side-effect management

Navigate nausea, constipation, and GI symptoms with proven strategies so you stay comfortable and consistent.

Data translation

Your care team turns lab results and symptoms into clear, actionable dose and lifestyle adjustments.

Sustainable habits

Build habits that protect your results long after you reach your goal weight.

Personalized titration built around you

GLP-1s affect everyone differently. We personalize how and when your dose changes based on your comfort, response, and goals—not a one-size-fits-all schedule.

Your starting dose is tailored to your history, prior GLP-1 use, and sensitivity so you can ease in comfortably and build a strong foundation.

We adjust your dose slowly to find the minimum effective dose that supports your goals and reduces the need for unnecessary increases.

Once your dose is optimized, we help you transition into a steady rhythm that supports stability, confidence, and sustainable progress.

If you reach a plateau or your goals change, we adjust your dose—up, down, or steady—to keep your treatment working for you.

We follow the latest GLP-1 research

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Supporting brain function

GLP-1s cross the blood–brain barrier and have been studied for effects on neuroinflammation, mood regulation, and cognitive resilience, with early evidence suggesting neuroprotective potential.

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Protecting cardiovascular health

Large outcome trials show reductions in major adverse cardiac events, linked to improved endothelial function, lower inflammation, and favorable lipid and blood pressure changes.

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Supporting kidney function

GLP-1s have been associated with reduced albuminuria and slower progression of diabetic kidney disease in some populations.

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Improving liver health

GLP-1s are well studied in NAFLD and NASH, with evidence showing reductions in liver fat and improvements in insulin sensitivity and liver enzymes.

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Supporting PCOS & fertility

GLP-1 therapy has been associated with improvements in insulin resistance, ovulatory function, and androgen levels in individuals with PCOS, with emerging evidence for fertility benefits.

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Reducing chronic inflammation

GLP-1 signaling has been linked to lower systemic inflammation, including reductions in CRP and improvements in endothelial and neuroinflammatory markers.

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Improving body composition

GLP-1s influence fat loss and visceral fat reduction while impacting appetite regulation and metabolic efficiency; preserving lean mass remains a key clinical consideration.

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Supporting respiratory health

Tirzepatide has been studied for weight-related obstructive sleep apnea, showing clinically meaningful reductions in apnea–hypopnea index.

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Patient reviews

Hear from our patients

Thorough explanation of my labs and a clear plan

I was impressed by how much detail I got during my consult. I have a comprehensive plan and a real understanding of what my results mean.

Kenji T.

Kenji T.

Third Avenue patient

Genuinely invested in my progress

My provider gave me all the time I needed and is clearly invested in helping me with my A1C and weight-loss journey.

Priya S.

Priya S.

Third Avenue patient

My trusted partner for long-term health

Since starting their research-backed protocols I have more energy, less pain, and improved biomarkers, especially around metabolic health.

Marcus J.

Marcus J.

Third Avenue patient

Frequently Asked Questions

Have more questions? Send us a message
How is Third Avenue different from a typical weight-loss clinic?

We treat GLP-1s as a tool for long-term metabolic health—not just the number on the scale. Your plan combines clinician-prescribed medication, personalized dosing, and ongoing support to protect muscle, support cardiometabolic health, and keep results going.

Will I be prescribed a GLP-1 through Third Avenue?

Eligibility is determined by a licensed Third Avenue clinician who reviews your medical history and goals. We don't rely on BMI alone—prescribing decisions are based on your overall metabolic and health needs.

What GLP-1 medications does Third Avenue offer?

Our clinicians prescribe GLP-1 treatments including semaglutide and tirzepatide when appropriate. If you're already on a GLP-1, we can also help support and optimize your existing treatment.

Do I need insurance to get started?

No. Third Avenue is a cash-pay service with transparent pricing, so you don't need insurance. Your plan includes the consultation, prescription, and medication with no hidden fees.

Can I join if I'm already taking a GLP-1?

Yes. If you're already prescribed a GLP-1 elsewhere, your Third Avenue care team can review your symptoms and response, provide coaching to improve outcomes, and guide dosing, tolerance, and long-term strategy.

What's included and how much does it cost?

Your plan is designed as ongoing medical care, not a one-time prescription. It includes clinician evaluation and prescribing, personalized dosing and titration over time, and continued oversight as your body responds—plus support for side effects, nutrition, and muscle preservation. Plans start at $99/mo.