Two ingredients support erectile blood flow
Sildenafil and tadalafil both support cGMP signaling during sexual stimulation. Their approved labels do not establish combined use, which may increase low-blood-pressure and adverse-effect risks.
Advanced Five-Ingredient Blend
Sildenafil + Tadalafil + Apomorphine + Bremelanotide + Oxytocin
A rapid-dissolve compounded tablet designed to address erectile response through five active ingredients and multiple physiologic pathways.
$49.00
Checkout does not guarantee a prescription. Medication is dispensed only after a licensed clinician determines treatment is appropriate. Your card statement will show “Third Ave”.
Licensed clinician review
Discreet delivery
Secure checkout
Erectile dysfunction is common, and established PDE5 treatments have helped many men improve their erections. Individual results vary, and a clinician will determine what is appropriate for you.
Get started88%
reported improved erections
Participants reporting improved erections with Viagra in cited clinical data. Results vary.
Pfizer: Viagra prescribing information82%
of men with ED and BPH
Reported improved erections with Cialis 20 mg in the cited clinical analysis. Results vary.
Lilly: Cialis clinical analysis52%
of men ages 40–70
Reported some degree of erectile dysfunction in the Massachusetts Male Aging Study.
U.S. Department of Veterans AffairsUnderstanding the formulation
Five ingredients spanning blood-flow and central signaling pathways.
Sildenafil and tadalafil support erectile blood flow, while apomorphine, bremelanotide, and oxytocin act through other physiologic pathways. Several ingredients have FDA-approved uses in different products or populations, but this combination is not FDA approved and requires especially careful clinician review.
Three ingredients add distinct pathways
Apomorphine is a dopamine agonist, bremelanotide is a melanocortin-receptor agonist, and oxytocin is a peptide hormone. Their FDA-approved labels do not establish this combined compounded use for erectile dysfunction.
Multi-ingredient review is essential
A clinician must assess cardiovascular status, blood pressure, nausea and fainting risk, drug interactions, and whether exposing you to every ingredient is appropriate.
View source
FDA: Understanding the Risks of Compounded DrugsActive ingredients
- Tadalafil 14–22 mg
- Sildenafil 40–110 mg
- Apomorphine HCl 2–3 mg
- Bremelanotide 1 mg
- Oxytocin 20 IU
Catalog directions
Take 1 tablet 30–60 minutes before sexual activity.
This is a compounded prescription formulation. Compounded drugs are not FDA approved. FDA-approved labeling for the individual ingredients does not establish safety or effectiveness of this five-ingredient combination.
Get startedPrivate from checkout to delivery
Your care is personal. Your purchase stays private.
Professional treatment should feel straightforward and respectful. We keep the experience discreet without making it feel secretive.
Discreet delivery
Medication ships in plain outer packaging with no treatment name or health information displayed.
A neutral statement
By the way, your credit card statement will show “Third Ave” — nothing referencing ED or your treatment.
Legitimate medical care
Every prescription requires review by a licensed clinician and is fulfilled only when medically appropriate.
What happens next
Professional care without the awkward waiting room.
Step 1
Choose your option
Select the strength, form, package, and purchase schedule that fit your preference. A clinician will still determine what is medically appropriate.
At checkoutStep 2
Complete a private intake
Share your health history, current medications, and goals through a secure medical questionnaire.
A few minutesStep 3
Clinician review
A U.S.-licensed clinician reviews your information, follows up when needed, and prescribes only when treatment is appropriate.
Typically within 72 hoursStep 4
Discreet fulfillment
If prescribed, a licensed pharmacy prepares your medication and ships it in plain outer packaging with tracking.
Tracking providedA purchase does not guarantee a prescription. Medication is dispensed only after a licensed clinician determines treatment is appropriate.
Why Third Avenue
Third Avenue
Typical experience
Privacy built into the process
Secure intake, discreet delivery, and a neutral Third Avenue billing descriptor.
Licensed clinical review
A clinician evaluates your health and medications before anything is prescribed.
Options without pressure
Compare strengths, forms, and schedules privately, then ask your care team questions.
Clear pricing
See the purchase price and schedule before checkout, with no ED wording on your statement.
Ongoing support
Your care team remains available for treatment questions, side effects, and adjustments.
Straight answers
Questions you can ask without judgment.
Clear information is part of good care. Your clinician can answer anything specific to your health.
Ask a private questionWhat is Advanced Five-Ingredient Blend?
It is a compounded prescription containing sildenafil 40 mg, tadalafil 20 mg, apomorphine HCl 2 mg, bremelanotide 1 mg, and oxytocin 20 IU. The combination is not FDA approved.
How do I take it?
Take one prescribed unit 30–60 minutes before sexual activity, following the pharmacy label for the exact dosage form. Do not combine it with other ED, arousal, or dopamine-active medication unless directed.
What side effects should I know about?
Possible effects include headache, flushing, indigestion, congestion, visual changes, nausea, vomiting, sleepiness, dizziness, blood-pressure changes, and skin darkening. Seek urgent care for chest pain, fainting, sudden vision or hearing changes, or an erection lasting more than four hours.
What should I tell my clinician?
Disclose nitrates or “poppers,” riociguat, 5-HT3 antagonists, other ED medication, uncontrolled high blood pressure, cardiovascular disease, fainting or sleep disorders, and every medicine or supplement.
What is compounding?
Compounding is when a licensed pharmacy prepares a medication for an individual prescription, such as combining ingredients or providing a different dosage form. Compounded drugs are not FDA approved, and FDA does not review them for safety, effectiveness, or quality before marketing.
What is erectile dysfunction?
Erectile dysfunction (ED) is the recurring difficulty getting or keeping an erection firm enough for sex. It is common and can have physical, medication-related, and psychological causes. A clinician can help identify an appropriate treatment approach.
Do I need insurance?
No. Third Avenue ED treatment can be purchased without insurance. You will see the price and purchase schedule before checkout.
Is my information safe?
We use secure systems and limit access to the information needed to provide your care. Your intake is private, delivery is discreet, and billing uses the neutral descriptor “Third Ave.”
Will the package reveal what I ordered?
No treatment name or health information appears on the plain outer package.
What appears on my credit card statement?
Your statement will show “Third Ave” — nothing that references ED or the medication.
Does checkout guarantee a prescription?
No. A licensed clinician must review your intake and determine that treatment is medically appropriate before medication can be dispensed.